I’ve been using only Comodo (CIS) as an active protection (mbam is my normal non-active or scan only protection). I’ve noticed that Microsoft has been pushing MSE (Microsoft Security Essentials) as an optional update and I was honestly thinking of trying it out but, I don’t want to risk it if the programs going to slow down my system or report any info non-anonymously. I expect a slight decrease in performance but, I want to know if it will be a noticeable difference. Other than CIS my computer also runs (constantly): WD Smartware Monitor thing (2 WD EHDD’s), Gadwin printscreen, Power Menu, Tomboy Notes, and Catalyst Control Center. I may also be running at any given time: Thunderbird, Firefox, Opera, uTorrent, Proxifier, your-freedom, + another program. My computer has a dual core processor running at 2.1GHz and 4 GB’s of PC6400 DDR2 RAM.
P.S. The only program mentioned up there that I’m not running at this moment is Opera and my computer is using no more than 50% processor (it’s fluctuating between 6% and 50%) and about 45% of my memory (RAM).