Firefox 1.5 Release Candidate 1 is due on 1st November, with the official Firefox 1.5 around mid-November. To help ensure a smooth transition it is a good idea to make sure your extensions and themes are up to date.
When Firefox 1.5 is first installed and run it will check to make sure the extensions and themes that you have installed are compatible. If they are not it will offer to search for updates and if none are found they will be disabled. I recommend that you check for updated extensions and themes before installing Firefox 1.5.
In Firefox 1.0.x select Tools>Options>Advanced for the option to check for updates to extensions and themes. This method is not 100% reliable and can miss an update.
You can check the homepage for the extension/theme or at Mozilla Update or The Extensions Mirror Forums for updated versions.
If you use Adblock then uninstall it and install Adblock Plus instead. Adblock is no longer being developed and will not work with Firefox 1.5
There will be some extensions and themes that are no longer being developed and will never work with Firefox 1.5, and others that will not be updated until after Firefox 1.5 is released.